IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation

Immunosuppressive and anti-cytokine treatment may have a protective effect for patients with COVID-19. Understanding the immune cell states shared between COVID-19 and other inflammatory diseases with established therapies may help nominate immunomodulatory therapies. Using an integrative strategy,...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Mears, Joseph R., Shakib, Lorien, Beynor, Jessica I., Shanaj, Sara, Korsunsky, Ilya, Nathan, Aparna, Donlin, Laura T., Raychaudhuri, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418716/
https://www.ncbi.nlm.nih.gov/pubmed/32793902
http://dx.doi.org/10.1101/2020.08.05.238360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418716/
https://www.ncbi.nlm.nih.gov/pubmed/32793902
http://dx.doi.org/10.1101/2020.08.05.238360

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