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A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

We describe the establishment and current content of the ImmuneCODE™ database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects exposed to or infected with the SARS-CoV-2 virus, as well as over 135,000 high-confidence SARS-CoV-2-specific TCRs. This data...

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Detalles Bibliográficos
Autores principales: Nolan, Sean, Vignali, Marissa, Klinger, Mark, Dines, Jennifer N., Kaplan, Ian M., Svejnoha, Emily, Craft, Tracy, Boland, Katie, Pesesky, Mitch, Gittelman, Rachel M., Snyder, Thomas M., Gooley, Christopher J., Semprini, Simona, Cerchione, Claudio, Mazza, Massimiliano, Delmonte, Ottavia M., Dobbs, Kerry, Carreño-Tarragona, Gonzalo, Barrio, Santiago, Sambri, Vittorio, Martinelli, Giovanni, Goldman, Jason D., Heath, James R., Notarangelo, Luigi D., Carlson, Jonathan M., Martinez-Lopez, Joaquin, Robins, Harlan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418738/
https://www.ncbi.nlm.nih.gov/pubmed/32793896
http://dx.doi.org/10.21203/rs.3.rs-51964/v1