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Two Stage Designs for Phase III Clinical Trials
Phase III platform trials are increasingly used to evaluate a sequence of treatments for a specific disease. Traditional approaches to structure such trials tend to focus on the sequential questions rather than the performance of the entire enterprise. We consider two-stage trials where an early eva...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418751/ https://www.ncbi.nlm.nih.gov/pubmed/32793927 http://dx.doi.org/10.1101/2020.07.29.20164525 |