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Two Stage Designs for Phase III Clinical Trials

Phase III platform trials are increasingly used to evaluate a sequence of treatments for a specific disease. Traditional approaches to structure such trials tend to focus on the sequential questions rather than the performance of the entire enterprise. We consider two-stage trials where an early eva...

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Detalles Bibliográficos
Autores principales: Follmann, Dean, Proschan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418751/
https://www.ncbi.nlm.nih.gov/pubmed/32793927
http://dx.doi.org/10.1101/2020.07.29.20164525