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Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity

BACKGROUND: Inflammation, oxidative stress, and apoptosis contribute to the evolution of doxorubicin (DOX)‐induced cardiotoxicity. Osteocrin (OSTN) is a novel secretory peptide mainly derived from the bone and skeletal muscle, and plays critical roles in regulating bone growth and physical endurance...

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Detalles Bibliográficos
Autores principales: Hu, Can, Zhang, Xin, Zhang, Ning, Wei, Wen‐Ying, Li, Ling‐Li, Ma, Zhen‐Guo, Tang, Qi‐Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418805/
https://www.ncbi.nlm.nih.gov/pubmed/32618439
http://dx.doi.org/10.1002/ctm2.124