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A review on the importance of genotyping and phenotyping in fluoropyrimidine treatment

Fluoropyrimidines, after more than 50 years from their discovery, are still the treatment of many types of cancer, and it is estimated that two million patients receive fluoropyrimidine therapy annually. The toxicity associated with fluoropyrimidines affects 30–40% of patients and some adverse effec...

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Detalles Bibliográficos
Autores principales: Deac, Andrada-Larisa, Burz, Claudia Cristina, Bocşe, Horea Florin, Bocşan, Ioana Corina, Buzoianu, Anca-Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418836/
https://www.ncbi.nlm.nih.gov/pubmed/32832886
http://dx.doi.org/10.15386/mpr-1564