Brain Testosterone-CYP1B1 (Cytochrome P450 1B1) Generated Metabolite 6β-Hydroxytestosterone Promotes Neurogenic Hypertension and Inflammation

Previously, we showed that peripheral administration of 6β-hydroxytestosterone, a CYP1B1 (cytochrome P450 1B1)-generated metabolite of testosterone, promotes angiotensin II-induced hypertension in male mice. However, the site of action and the underlying mechanism by which 6β-hydroxytestosterone con...

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Detalles Bibliográficos
Autores principales: Singh, Purnima, Dutta, Shubha Ranjan, Song, Chi Young, Oh, SaeRam, Gonzalez, Frank J., Malik, Kafait U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418933/
https://www.ncbi.nlm.nih.gov/pubmed/32755412
http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418933/
https://www.ncbi.nlm.nih.gov/pubmed/32755412
http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15567

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