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Brain Testosterone-CYP1B1 (Cytochrome P450 1B1) Generated Metabolite 6β-Hydroxytestosterone Promotes Neurogenic Hypertension and Inflammation

Previously, we showed that peripheral administration of 6β-hydroxytestosterone, a CYP1B1 (cytochrome P450 1B1)-generated metabolite of testosterone, promotes angiotensin II-induced hypertension in male mice. However, the site of action and the underlying mechanism by which 6β-hydroxytestosterone con...

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Detalles Bibliográficos
Autores principales:	Singh, Purnima, Dutta, Shubha Ranjan, Song, Chi Young, Oh, SaeRam, Gonzalez, Frank J., Malik, Kafait U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418933/ https://www.ncbi.nlm.nih.gov/pubmed/32755412 http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.15567

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