Non-invasive monitoring of drug action: A new live in vitro assay design for Chagas’ disease drug discovery

New assay designs are needed to improve the predictive value of the Trypanosoma cruzi in vitro tests used as part of the Chagas' disease drug development pipeline. Here, we employed a green fluorescent protein (eGFP)-expressing parasite line and live high-content imaging to monitor the growth o...

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Detalles Bibliográficos
Autores principales: Fesser, Anna F., Braissant, Olivier, Olmo, Francisco, Kelly, John M., Mäser, Pascal, Kaiser, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419005/
https://www.ncbi.nlm.nih.gov/pubmed/32716934
http://dx.doi.org/10.1371/journal.pntd.0008487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419005/
https://www.ncbi.nlm.nih.gov/pubmed/32716934
http://dx.doi.org/10.1371/journal.pntd.0008487

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