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Non-invasive monitoring of drug action: A new live in vitro assay design for Chagas’ disease drug discovery
New assay designs are needed to improve the predictive value of the Trypanosoma cruzi in vitro tests used as part of the Chagas' disease drug development pipeline. Here, we employed a green fluorescent protein (eGFP)-expressing parasite line and live high-content imaging to monitor the growth o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419005/ https://www.ncbi.nlm.nih.gov/pubmed/32716934 http://dx.doi.org/10.1371/journal.pntd.0008487 |