Cargando…

Targeting of cancer stem cells by differentiation therapy

Chemoresistance is a hallmark of cancer stem cells (CSCs). To develop novel therapeutic strategies that target CSCs, we established osteosarcoma‐initiating (OSi) cells by introducing the c‐Myc gene into bone marrow stromal cells derived from Ink4a/Arf KO mice. These OSi cells include bipotent commit...

Descripción completa

Detalles Bibliográficos
Autores principales: Arima, Yoshimi, Nobusue, Hiroyuki, Saya, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419023/
https://www.ncbi.nlm.nih.gov/pubmed/32462706
http://dx.doi.org/10.1111/cas.14504