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HS2ST1‐dependent signaling pathways determine breast cancer cell viability, matrix interactions, and invasive behavior

Heparan sulfate proteoglycans (HSPGs) act as signaling co‐receptors by interaction of their sulfated glycosaminoglycan chains with numerous signaling molecules. In breast cancer, the function of heparan sulfate 2‐O‐sulfotransferase (HS2ST1), the enzyme mediating 2‐O‐sulfation of HS, is largely unkno...

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Detalles Bibliográficos
Autores principales: Vijaya Kumar, Archana, Brézillon, Stéphane, Untereiner, Valérie, Sockalingum, Ganesh Dhruvananda, Kumar Katakam, Sampath, Mohamed, Hossam Taha, Kemper, Björn, Greve, Burkhard, Mohr, Benedikt, Ibrahim, Sherif Abdelaziz, Goycoolea, Francisco M., Kiesel, Ludwig, Pavão, Mauro S.G., Motta, Juliana M., Götte, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419026/
https://www.ncbi.nlm.nih.gov/pubmed/32573871
http://dx.doi.org/10.1111/cas.14539