Dual TTK/CLK2 inhibitor, CC‐671, selectively antagonizes ABCG2‐mediated multidrug resistance in lung cancer cells

One pivotal factor that leads to multidrug resistance (MDR) is the overexpression of ABCG2. Therefore, tremendous effort has been devoted to the search of effective reversal agents to overcome ABCG2‐mediated MDR. CC‐671 is a potent and selective inhibitor of both TTK (human protein kinase monopolar...

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Detalles Bibliográficos
Autores principales: Wu, Zhuo‐Xun, Yang, Yuqi, Wang, Guangsuo, Wang, Jing‐Quan, Teng, Qiu‐Xu, Sun, Lingling, Lei, Zi‐Ning, Lin, Lizhu, Chen, Zhe‐Sheng, Zou, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419038/
https://www.ncbi.nlm.nih.gov/pubmed/32478948
http://dx.doi.org/10.1111/cas.14505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419038/
https://www.ncbi.nlm.nih.gov/pubmed/32478948
http://dx.doi.org/10.1111/cas.14505

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