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Soluble Vegfr3 gene therapy suppresses multi‐organ metastasis in a mouse mammary cancer model

Accumulating evidence on the association of VEGF‐C with lymphangiogenesis and lymph node metastasis implicates lymphatic vessels as a potential target in anti‐cancer therapy. To evaluate whether blocking VEGF‐C and VEGFR‐3 signaling can inhibit multi‐organ metastases, a mouse metastatic mammary canc...

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Detalles Bibliográficos
Autores principales: Shibata, Masa‐Aki, Shibata, Eiko, Tanaka, Yoshihisa, Shiraoka, Chinatsu, Kondo, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419054/
https://www.ncbi.nlm.nih.gov/pubmed/32539229
http://dx.doi.org/10.1111/cas.14531