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Structure-based enzyme engineering improves donor-substrate recognition of Arabidopsis thaliana glycosyltransferases

Glycosylation of secondary metabolites involves plant UDP-dependent glycosyltransferases (UGTs). UGTs have shown promise as catalysts in the synthesis of glycosides for medical treatment. However, limited understanding at the molecular level due to insufficient biochemical and structural information...

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Detalles Bibliográficos
Autores principales: Akere, Aishat, Chen, Serena H., Liu, Xiaohan, Chen, Yanger, Dantu, Sarath Chandra, Pandini, Alessandro, Bhowmik, Debsindhu, Haider, Shozeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419078/
https://www.ncbi.nlm.nih.gov/pubmed/32657326
http://dx.doi.org/10.1042/BCJ20200477