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MARCH8 inhibits viral infection by two different mechanisms

Membrane-associated RING-CH 8 (MARCH8) inhibits infection with both HIV-1 and vesicular stomatitis virus G-glycoprotein (VSV-G)-pseudotyped viruses by reducing virion incorporation of envelope glycoproteins. The molecular mechanisms by which MARCH8 targets envelope glycoproteins remain unknown. Here...

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Detalles Bibliográficos
Autores principales: Zhang, Yanzhao, Tada, Takuya, Ozono, Seiya, Kishigami, Satoshi, Fujita, Hideaki, Tokunaga, Kenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419139/
https://www.ncbi.nlm.nih.gov/pubmed/32778221
http://dx.doi.org/10.7554/eLife.57763