Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets

The filarial nematode Brugia malayi represents a leading cause of disability in the developing world, causing lymphatic filariasis in nearly 40 million people. Currently available drugs are not well-suited to mass drug administration efforts, so new treatments are urgently required. One potential vu...

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Detalles Bibliográficos
Autores principales: Curran, David M, Grote, Alexandra, Nursimulu, Nirvana, Geber, Adam, Voronin, Dennis, Jones, Drew R, Ghedin, Elodie, Parkinson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419141/
https://www.ncbi.nlm.nih.gov/pubmed/32779567
http://dx.doi.org/10.7554/eLife.51850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419141/
https://www.ncbi.nlm.nih.gov/pubmed/32779567
http://dx.doi.org/10.7554/eLife.51850

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