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Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets
The filarial nematode Brugia malayi represents a leading cause of disability in the developing world, causing lymphatic filariasis in nearly 40 million people. Currently available drugs are not well-suited to mass drug administration efforts, so new treatments are urgently required. One potential vu...
Autores principales: | Curran, David M, Grote, Alexandra, Nursimulu, Nirvana, Geber, Adam, Voronin, Dennis, Jones, Drew R, Ghedin, Elodie, Parkinson, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419141/ https://www.ncbi.nlm.nih.gov/pubmed/32779567 http://dx.doi.org/10.7554/eLife.51850 |
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