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Retrospective review of outcomes in patients with DNA-damage repair related pancreatic cancer

BACKGROUND: Patients with DNA-damage response genes (DDR)-related pancreas cancer (BRCA1/2 or other DNA-damage related genes) may have improved outcomes secondary to increased sensitivity to DNA-damaging drugs (platinum chemotherapy/ poly ADP ribose polymerase (PARP)-inhibitors). However, data is sc...

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Detalles Bibliográficos
Autores principales: Macklin-Mantia, Sarah K., Hines, Stephanie L., Kasi, Pashtoon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419180/
https://www.ncbi.nlm.nih.gov/pubmed/32793315
http://dx.doi.org/10.1186/s13053-020-00148-9