IκB kinase-ε-mediated phosphorylation triggers IRF-1 degradation in breast cancer cells

Interferon Regulatory Factors (IRFs) are key regulators of immunity, cell survival and apoptosis. IRF transcriptional activity and subcellular localization are tightly regulated by posttranscriptional modifications including phosphorylation. The IκB kinase family member IKK-ε is essential in regulat...

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Detalles Bibliográficos
Autores principales: Remoli, Anna Lisa, Sgarbanti, Marco, Perrotti, Edvige, Acchioni, Marta, Orsatti, Roberto, Acchioni, Chiara, Battistini, Angela, Clarke, Robert, Marsili, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419274/
https://www.ncbi.nlm.nih.gov/pubmed/32784074
http://dx.doi.org/10.1016/j.neo.2020.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419274/
https://www.ncbi.nlm.nih.gov/pubmed/32784074
http://dx.doi.org/10.1016/j.neo.2020.07.004

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