Metformin reduces saturated fatty acid-induced lipid accumulation and inflammatory response by restoration of autophagic flux in endothelial cells

Autophagy, an integral part of the waste recycling process, plays an important role in cellular physiology and pathophysiology. Impaired autophagic flux causes ectopic lipid deposition, which is defined as the accumulation of lipids in non-adipose tissue. Ectopic lipid accumulation is observed in pa...

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Detalles Bibliográficos
Autores principales: Kim, Hae-Suk, Ren, Guang, Kim, Teayoun, Bhatnagar, Sushant, Yang, Qinglin, Bahk, Young Yil, Kim, Jeong-a
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419289/
https://www.ncbi.nlm.nih.gov/pubmed/32782332
http://dx.doi.org/10.1038/s41598-020-70347-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419289/
https://www.ncbi.nlm.nih.gov/pubmed/32782332
http://dx.doi.org/10.1038/s41598-020-70347-w

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