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Metformin reduces saturated fatty acid-induced lipid accumulation and inflammatory response by restoration of autophagic flux in endothelial cells
Autophagy, an integral part of the waste recycling process, plays an important role in cellular physiology and pathophysiology. Impaired autophagic flux causes ectopic lipid deposition, which is defined as the accumulation of lipids in non-adipose tissue. Ectopic lipid accumulation is observed in pa...
Autores principales: | Kim, Hae-Suk, Ren, Guang, Kim, Teayoun, Bhatnagar, Sushant, Yang, Qinglin, Bahk, Young Yil, Kim, Jeong-a |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419289/ https://www.ncbi.nlm.nih.gov/pubmed/32782332 http://dx.doi.org/10.1038/s41598-020-70347-w |
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