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Using NMR spectroscopy to investigate the role played by copper in prion diseases
Prion diseases are a group of rare neurodegenerative disorders that develop as a result of the conformational conversion of normal prion protein (PrP(C)) to the disease-associated isoform (PrP(Sc)). The mechanism that actually causes disease remains unclear. However, the mechanism underlying the con...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419355/ https://www.ncbi.nlm.nih.gov/pubmed/32328835 http://dx.doi.org/10.1007/s10072-020-04321-9 |