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Murine Thigh Microdialysis to Evaluate the Pharmacokinetic/Pharmacodynamic Integration of Cefquinome Against Actinobacillus pleuropneumoniae

This study aimed to explore the application of microdialysis in pharmacokinetic (PK)/pharmacodynamic (PD) integration of cefquinome against Actinobacillus pleuropneumoniae. After the A. pleuropneumoniae population reached 10(6) CFU/thigh, the mice received 0.04, 0.16, 0.63, 2.5, and 10 mg/kg cefquin...

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Detalles Bibliográficos
Autores principales: Zhang, Longfei, Zhou, Zichong, Gu, Xiaoyan, Huang, Sixiu, Shen, Xiangguang, Ding, Huanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419427/
https://www.ncbi.nlm.nih.gov/pubmed/32851028
http://dx.doi.org/10.3389/fvets.2020.00448