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Multidrug-related protein 1 (MRP1) polymorphisms rs129081, rs212090, and rs212091 predict survival in normal karyotype acute myeloid leukemia

Resistant disease is still a main obstacle in acute myeloid leukemia (AML) treatment. Therefore, individual genetic variations affecting therapy response are gaining increasing importance. Both SNPs and ABC transporter genes could already be associated with drug resistance. Here, we report allelic v...

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Detalles Bibliográficos
Autores principales: Kunadt, Desiree, Dransfeld, Christian, Dill, Claudia, Schmiedgen, Maria, Kramer, Michael, Altmann, Heidi, Röllig, Christoph, Bornhäuser, Martin, Mahlknecht, Ulrich, Schaich, Markus, Stölzel, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419446/
https://www.ncbi.nlm.nih.gov/pubmed/32621177
http://dx.doi.org/10.1007/s00277-020-04163-7