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Efficient variance components analysis across millions of genomes

While variance components analysis has emerged as a powerful tool in complex trait genetics, existing methods for fitting variance components do not scale well to large-scale datasets of genetic variation. Here, we present a method for variance components analysis that is accurate and efficient: cap...

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Detalles Bibliográficos
Autores principales: Pazokitoroudi, Ali, Wu, Yue, Burch, Kathryn S., Hou, Kangcheng, Zhou, Aaron, Pasaniuc, Bogdan, Sankararaman, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419517/
https://www.ncbi.nlm.nih.gov/pubmed/32782262
http://dx.doi.org/10.1038/s41467-020-17576-9