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Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial intervention

Intracellular pathogens mobilize host signaling pathways of their host cell to promote their own survival. Evidence is emerging that signal transduction elements are activated in a-nucleated erythrocytes in response to infection with malaria parasites, but the extent of this phenomenon remains unkno...

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Detalles Bibliográficos
Autores principales: Adderley, Jack D., John von Freyend, Simona, Jackson, Sarah A., Bird, Megan J., Burns, Amy L., Anar, Burcu, Metcalf, Tom, Semblat, Jean-Philippe, Billker, Oliver, Wilson, Danny W., Doerig, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419518/
https://www.ncbi.nlm.nih.gov/pubmed/32782246
http://dx.doi.org/10.1038/s41467-020-17829-7