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Human Aging Alters the Spatial Organization between CD34+ Hematopoietic Cells and Adipocytes in Bone Marrow

Age-related clonal hematopoiesis is a major risk factor for myeloid malignancy and myeloid skewing is a hallmark of aging. However, while it is known that non-cell-autonomous components of the microenvironment can also influence this risk, there have been few studies of how the spatial architecture...

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Detalles Bibliográficos
Autores principales: Aguilar-Navarro, Alicia G., Meza-León, Berenice, Gratzinger, Dita, Juárez-Aguilar, Fany G., Chang, Qing, Ornatsky, Olga, Tsui, Hubert, Esquivel-Gómez, Ricardo, Hernández-Ramírez, Antonio, Xie, Stephanie Z., Dick, John E., Flores-Figueroa, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419665/
https://www.ncbi.nlm.nih.gov/pubmed/32649902
http://dx.doi.org/10.1016/j.stemcr.2020.06.011