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Human Aging Alters the Spatial Organization between CD34+ Hematopoietic Cells and Adipocytes in Bone Marrow
Age-related clonal hematopoiesis is a major risk factor for myeloid malignancy and myeloid skewing is a hallmark of aging. However, while it is known that non-cell-autonomous components of the microenvironment can also influence this risk, there have been few studies of how the spatial architecture...
Autores principales: | Aguilar-Navarro, Alicia G., Meza-León, Berenice, Gratzinger, Dita, Juárez-Aguilar, Fany G., Chang, Qing, Ornatsky, Olga, Tsui, Hubert, Esquivel-Gómez, Ricardo, Hernández-Ramírez, Antonio, Xie, Stephanie Z., Dick, John E., Flores-Figueroa, Eugenia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419665/ https://www.ncbi.nlm.nih.gov/pubmed/32649902 http://dx.doi.org/10.1016/j.stemcr.2020.06.011 |
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