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Dual Targeting to Overcome Current Challenges in Multiple Myeloma CAR T-Cell Treatment

In the era of highly promising novel targeted-immunotherapy strategies for multiple myeloma (MM), the first series of clinical trials with CAR T-cells targeting the plasma cell-specific B-cell maturation antigen (BCMA) have shown excellent response rates. In the long-term, however, MM appears to esc...

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Detalles Bibliográficos
Autores principales: van der Schans, Jort J., van de Donk, Niels W. C. J., Mutis, Tuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419675/
https://www.ncbi.nlm.nih.gov/pubmed/32850436
http://dx.doi.org/10.3389/fonc.2020.01362