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Primary Ciliary Deficits in the Dentate Gyrus of Fragile X Syndrome
The primary cilium is the non-motile cilium present in most mammalian cell types and functions as an antenna for cells to sense signals. Ablating primary cilia in postnatal newborn neurons of the dentate gyrus (DG) results in both reduced dendritic arborization and synaptic strength, leading to hipp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419715/ https://www.ncbi.nlm.nih.gov/pubmed/32735823 http://dx.doi.org/10.1016/j.stemcr.2020.07.001 |