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Conversion of Fibroblast into Functional Leydig-like Cell Using Defined Small Molecules

Recent studies have demonstrated that fibroblasts can be directly converted into functional Leydig cells by transcription factors. However, the transgenic approach used in these studies raises safety concerns for its future application. Here, we report that fibroblasts can be directly reprogrammed i...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Zhou, Chenxing, Zhang, Tiantian, Li, Quan, Mei, Jiaxin, Liang, Jinlian, Li, Ziyi, Li, Hanhao, Xiang, Qi, Zhang, Qihao, Zhang, Lei, Huang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419716/
https://www.ncbi.nlm.nih.gov/pubmed/32735821
http://dx.doi.org/10.1016/j.stemcr.2020.07.002