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Conversion of Fibroblast into Functional Leydig-like Cell Using Defined Small Molecules
Recent studies have demonstrated that fibroblasts can be directly converted into functional Leydig cells by transcription factors. However, the transgenic approach used in these studies raises safety concerns for its future application. Here, we report that fibroblasts can be directly reprogrammed i...
Autores principales: | Yang, Yan, Zhou, Chenxing, Zhang, Tiantian, Li, Quan, Mei, Jiaxin, Liang, Jinlian, Li, Ziyi, Li, Hanhao, Xiang, Qi, Zhang, Qihao, Zhang, Lei, Huang, Yadong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419716/ https://www.ncbi.nlm.nih.gov/pubmed/32735821 http://dx.doi.org/10.1016/j.stemcr.2020.07.002 |
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