The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver

We earlier showed that outside-in integrin signaling through POSTN-ITGAV interaction plays an important role in regulating adult hematopoietic stem cell (HSC) quiescence. Here, we show that Itgav deletion results in increased frequency of phenotypic HSCs in fetal liver (FL) due to faster proliferati...

Descripción completa

Detalles Bibliográficos
Autores principales: Biswas, Atreyi, Roy, Irene M., Babu, Prathibha C., Manesia, Javed, Schouteden, Sarah, Vijayakurup, Vinod, Anto, Ruby John, Huelsken, Joerg, Lacy-Hulbert, Adam, Verfaillie, Catherine M., Khurana, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419718/
https://www.ncbi.nlm.nih.gov/pubmed/32735820
http://dx.doi.org/10.1016/j.stemcr.2020.06.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7419718/
https://www.ncbi.nlm.nih.gov/pubmed/32735820
http://dx.doi.org/10.1016/j.stemcr.2020.06.022

Ejemplares similares