Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting

Human retromer, a heterotrimer of VPS26 (VPS26A or VPS26B), VPS35 and VPS29, orchestrates the endosomal retrieval of internalised cargo and promotes their cell surface recycling, a prototypical cargo being the glucose transporter GLUT1 (also known as SLC2A1). The role of retromer in the retrograde s...

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Detalles Bibliográficos
Autores principales: Evans, Ashley J., Daly, James L., Anuar, Anis N. K., Simonetti, Boris, Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7420817/
https://www.ncbi.nlm.nih.gov/pubmed/32747499
http://dx.doi.org/10.1242/jcs.246033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7420817/
https://www.ncbi.nlm.nih.gov/pubmed/32747499
http://dx.doi.org/10.1242/jcs.246033

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