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Mechanisms of drug interactions between translation-inhibiting antibiotics
Antibiotics that interfere with translation, when combined, interact in diverse and difficult-to-predict ways. Here, we explain these interactions by “translation bottlenecks”: points in the translation cycle where antibiotics block ribosomal progression. To elucidate the underlying mechanisms of dr...
Autores principales: | Kavčič, Bor, Tkačik, Gašper, Bollenbach, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421507/ https://www.ncbi.nlm.nih.gov/pubmed/32782250 http://dx.doi.org/10.1038/s41467-020-17734-z |
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