Predicting the chemical space of fungal polyketides by phylogeny-based bioinformatics analysis of polyketide synthase-nonribosomal peptide synthetase and its modification enzymes

Fungal polyketide synthase (PKS)–nonribosomal peptide synthetase (NRPS) hybrids are key enzymes for synthesizing structurally diverse hybrid natural products (NPs) with characteristic biological activities. Predicting their chemical space is of particular importance in the field of natural product c...

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Detalles Bibliográficos
Autores principales: Minami, Atsushi, Ugai, Takahiro, Ozaki, Taro, Oikawa, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421883/
https://www.ncbi.nlm.nih.gov/pubmed/32782278
http://dx.doi.org/10.1038/s41598-020-70177-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7421883/
https://www.ncbi.nlm.nih.gov/pubmed/32782278
http://dx.doi.org/10.1038/s41598-020-70177-w

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