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Overcoming the limitations of locally administered oncolytic virotherapy

Adenovirus (Ad) has been most extensively evaluated gene transfer vector in clinical trials due to facile production in high viral titer, highly efficient transduction, and proven safety record. Similarly, an oncolytic Ad, which replicates selectively in cancer cells through genetic modifications, i...

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Detalles Bibliográficos
Autores principales: Hong, JinWoo, Yun, Chae-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422506/
https://www.ncbi.nlm.nih.gov/pubmed/32903299
http://dx.doi.org/10.1186/s42490-019-0016-x