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POLE2 knockdown reduce tumorigenesis in esophageal squamous cells
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors originated from digestive system around the world and the treatment was limited by the unclear mechanism. DNA polymerase epsilon 2, accessory subunit (POLE2) is involved in DNA replication, repair, and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422519/ https://www.ncbi.nlm.nih.gov/pubmed/32831648 http://dx.doi.org/10.1186/s12935-020-01477-4 |