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POLE2 knockdown reduce tumorigenesis in esophageal squamous cells

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors originated from digestive system around the world and the treatment was limited by the unclear mechanism. DNA polymerase epsilon 2, accessory subunit (POLE2) is involved in DNA replication, repair, and...

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Detalles Bibliográficos
Autores principales: Zhu, Yongjun, Chen, Gang, Song, Yang, Chen, Zhiming, Chen, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422519/
https://www.ncbi.nlm.nih.gov/pubmed/32831648
http://dx.doi.org/10.1186/s12935-020-01477-4