Kinetic Resolution of Racemic Primary Amines Using Geobacillus stearothermophilus Amine Dehydrogenase Variant

A NADH‐dependent engineered amine dehydrogenase from Geobacillus stearothermophilus (LE‐AmDH‐v1) was applied together with a NADH‐oxidase from Streptococcus mutans (NOx) for the kinetic resolution of pharmaceutically relevant racemic α‐chiral primary amines. The reaction conditions (e. g., pH, tempe...

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Detalles Bibliográficos
Autores principales: Tseliou, Vasilis, Knaus, Tanja, Vilím, Jan, Masman, Marcelo F., Mutti, Francesco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422701/
https://www.ncbi.nlm.nih.gov/pubmed/32802214
http://dx.doi.org/10.1002/cctc.201902085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422701/
https://www.ncbi.nlm.nih.gov/pubmed/32802214
http://dx.doi.org/10.1002/cctc.201902085

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