Cargando…

Kinetic Resolution of Racemic Primary Amines Using Geobacillus stearothermophilus Amine Dehydrogenase Variant

A NADH‐dependent engineered amine dehydrogenase from Geobacillus stearothermophilus (LE‐AmDH‐v1) was applied together with a NADH‐oxidase from Streptococcus mutans (NOx) for the kinetic resolution of pharmaceutically relevant racemic α‐chiral primary amines. The reaction conditions (e. g., pH, tempe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tseliou, Vasilis, Knaus, Tanja, Vilím, Jan, Masman, Marcelo F., Mutti, Francesco G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422701/ https://www.ncbi.nlm.nih.gov/pubmed/32802214 http://dx.doi.org/10.1002/cctc.201902085

Ejemplares similares

Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines
por: Tseliou, Vasilis, et al.
Publicado: (2019)

Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity
por: Tseliou, Vasilis, et al.
Publicado: (2020)

Generation of amine dehydrogenases with increased catalytic performance and substrate scope from ε-deaminating L-Lysine dehydrogenase
por: Tseliou, Vasilis, et al.
Publicado: (2019)

Continuous Flow Biocatalytic Reductive Amination by Co‐Entrapping Dehydrogenases with Agarose Gel in a 3D‐Printed Mould Reactor
por: Croci, Federico, et al.
Publicado: (2022)

Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds
por: Knaus, Tanja, et al.
Publicado: (2017)

Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate
por: Cameron, Scott, et al.
Publicado: (2009)

Insights into the Geobacillus stearothermophilus species based on phylogenomic principles
por: Burgess, S. A., et al.
Publicado: (2017)

From Racemic Alcohols to Enantiopure Amines: Ru-Catalyzed Diastereoselective Amination
por: Oldenhuis, Nathan J., et al.
Publicado: (2014)

Kinetics of Germination of Individual Spores of Geobacillus stearothermophilus as Measured by Raman Spectroscopy and Differential Interference Contrast Microscopy
por: Zhou, Tingting, et al.
Publicado: (2013)

Thermal Adaptation of Dihydrofolate Reductase from the Moderate Thermophile Geobacillus stearothermophilus
por: Guo, Jiannan, et al.
Publicado: (2014)

Efficient synthesis of enantiopure amines from alcohols using resting E. coli cells and ammonia†
por: Houwman, Joseline A., et al.
Publicado: (2019)

Starch biotransformation into isomaltooligosaccharides using thermostable alpha-glucosidase from Geobacillus stearothermophilus
por: Chen, Peng, et al.
Publicado: (2018)

Role of Cys73 in the thermostability of farnesyl diphosphate synthase from Geobacillus stearothermophilus
por: Samori, Petrus Yesaya, et al.
Publicado: (2017)

Decontamination of Geobacillus Stearothermophilus using the Arca Aerosolized Hydrogen Peroxide decontamination system
por: Mead, Loren Benjamin, et al.
Publicado: (2022)

Structural Basis of Substrate Binding in WsaF, a Rhamnosyltransferase from Geobacillus stearothermophilus
por: Steiner, Kerstin, et al.
Publicado: (2010)

Expression and Characterization of Geobacillus stearothermophilus SR74 Recombinant α-Amylase in Pichia pastoris
por: Gandhi, Sivasangkary, et al.
Publicado: (2015)

One-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate
por: Knaus, Tanja, et al.
Publicado: (2022)

Screening primary racemic amines for enantioseparation by derivatized polysaccharide and cyclofructan columns()
por: Lim, Yeeun, et al.
Publicado: (2016)

Translation activity of chimeric ribosomes composed of Escherichia coli and Bacillus subtilis or Geobacillus stearothermophilus subunits
por: Tsuji, Sayaka, et al.
Publicado: (2017)

The structure of His-tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a ‘spanner in the works’
por: Given, Fiona M., et al.
Publicado: (2022)

Comparative Genomic Analysis of a Thermophilic Protease-Producing Strain Geobacillus stearothermophilus H6
por: Lai, Ruilin, et al.
Publicado: (2023)

Catalytic Promiscuity of Galactose Oxidase: A Mild Synthesis of Nitriles from Alcohols, Air, and Ammonia
por: Vilím, Jan, et al.
Publicado: (2018)

PQQ‐dependent Dehydrogenase Enables One‐pot Bi‐enzymatic Enantio‐convergent Biocatalytic Amination of Racemic sec‐Allylic Alcohols
por: Gandomkar, Somayyeh, et al.
Publicado: (2020)

Comparison of pulsed light inactivation kinetics and modeling of Escherichia coli (ATCC-29055), Clostridium sporogenes (ATCC-7955) and Geobacillus stearothermophilus (ATCC-10149)
por: John, Dalia, et al.
Publicado: (2020)

Crystallization and preliminary crystallographic analysis of Axe2, an acetylxylan esterase from Geobacillus stearothermophilus. Corrigendum
por: Lansky, Shifra, et al.
Publicado: (2014)

Structural insights into the specific interaction between Geobacillus stearothermophilus tryptophanyl-tRNA synthetase and antimicrobial Chuangxinmycin
por: Fan, Shuai, et al.
Publicado: (2022)

LysGR1, a novel thermostable endolysin from Geobacillus stearothermophilus bacteriophage GR1
por: Choi, Dahee, et al.
Publicado: (2023)

Thermostable homologues of the periplasmic siderophore-binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius
por: Blagova, Elena V., et al.
Publicado: (2023)

Hydrogen‐Borrowing Alcohol Bioamination with Coimmobilized Dehydrogenases
por: Böhmer, Wesley, et al.
Publicado: (2018)

Direct fermentation of potato starch and potato residues to lactic acid by Geobacillus stearothermophilus under non-sterile conditions
por: Smerilli, Marina, et al.
Publicado: (2015)

Draft Genome Sequences of Three Strains of Geobacillus stearothermophilus Isolated from a Milk Powder Manufacturing Plant
por: Burgess, Sara A., et al.
Publicado: (2015)

Whole-Genome Sequences of Five Geobacillus stearothermophilus Strains Isolated from Processing Lines of Powdered Infant Formula
por: Cho, Tae Jin, et al.
Publicado: (2019)

Molecular Engineering of the Geobacillus stearothermophilus α-Amylase and Cel5E from Chlostridium thermocellim; In Silico Approach
por: Torktaz, Ibrahim, et al.
Publicado: (2018)

Transaminase‐Catalyzed Racemization with Potential for Dynamic Kinetic Resolutions
por: Ruggieri, Federica, et al.
Publicado: (2018)

Kinetic Resolution of Racemic Mixtures via Enantioselective Photocatalysis
por: Arbell, Nitai, et al.
Publicado: (2021)

Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons
por: Al-Hassan, Jassim M., et al.
Publicado: (2011)

Submerged Bioreactor Production of Geobacillus stearothermophilus ATCC 7953 Spores for Use as Bioindicators to Validate Hydrogen Peroxide Inactivation Processes
por: Stier, Philipp, et al.
Publicado: (2021)

Highly efficient production of chiral amines in batch and continuous flow by immobilized ω-transaminases on controlled porosity glass metal-ion affinity carrier
por: Böhmer, Wesley, et al.
Publicado: (2019)

Enhancement of Polymerase Activity of the Large Fragment in DNA Polymerase I from Geobacillus stearothermophilus by Site-Directed Mutagenesis at the Active Site
por: Ma, Yi, et al.
Publicado: (2016)

Genome Sequence of Geobacillus stearothermophilus DSM 458, an Antimicrobial-Producing Thermophilic Bacterium, Isolated from a Sugar Beet Factory
por: Egan, Kevin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lnuud102flf6nosj8fel8tso73