Derivatization and combination therapy of current COVID-19 therapeutic agents: a review of mechanistic pathways, adverse effects, and binding sites

Current treatment of patients with coronavirus 2019 (COVID-19) involves repurposed drugs that inhibit viral infection by either binding to their respective targets or via modulating cellular signal transduction. However, there is still a great deal of efficacy enhancement through combination therapy...

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Detalles Bibliográficos
Autores principales: El Kantar, Sally, Nehmeh, Bilal, Saad, Philippe, Mitri, Gabie, Estephan, Celine, Mroueh, Mohamad, Akoury, Elias, Taleb, Robin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422796/
https://www.ncbi.nlm.nih.gov/pubmed/32801052
http://dx.doi.org/10.1016/j.drudis.2020.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422796/
https://www.ncbi.nlm.nih.gov/pubmed/32801052
http://dx.doi.org/10.1016/j.drudis.2020.08.002

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