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Derivatization and combination therapy of current COVID-19 therapeutic agents: a review of mechanistic pathways, adverse effects, and binding sites
Current treatment of patients with coronavirus 2019 (COVID-19) involves repurposed drugs that inhibit viral infection by either binding to their respective targets or via modulating cellular signal transduction. However, there is still a great deal of efficacy enhancement through combination therapy...
Autores principales: | El Kantar, Sally, Nehmeh, Bilal, Saad, Philippe, Mitri, Gabie, Estephan, Celine, Mroueh, Mohamad, Akoury, Elias, Taleb, Robin I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422796/ https://www.ncbi.nlm.nih.gov/pubmed/32801052 http://dx.doi.org/10.1016/j.drudis.2020.08.002 |
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