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Repurposing of existing FDA approved drugs for Neprilysin inhibition: An in-silico study
Neprilysin (NEP) is a neutral endopeptidase with diverse physiological roles in the body. NEP's role in degradation of diverse classes of peptides such as amyloid beta, natriuretic peptide, substance P, angiotensin, endothelins, etc., is associated with pathologies of alzheimer's, kidney a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422802/ https://www.ncbi.nlm.nih.gov/pubmed/32834116 http://dx.doi.org/10.1016/j.molstruc.2020.129073 |