Cargando…
Repurposing of existing FDA approved drugs for Neprilysin inhibition: An in-silico study
Neprilysin (NEP) is a neutral endopeptidase with diverse physiological roles in the body. NEP's role in degradation of diverse classes of peptides such as amyloid beta, natriuretic peptide, substance P, angiotensin, endothelins, etc., is associated with pathologies of alzheimer's, kidney a...
Autores principales: | Sankhe, Runali, Rathi, Ekta, Manandhar, Suman, Kumar, Avinash, Pai, Sreedhara Ranganath K, Kini, Suvarna G, Kishore, Anoop |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422802/ https://www.ncbi.nlm.nih.gov/pubmed/32834116 http://dx.doi.org/10.1016/j.molstruc.2020.129073 |
Ejemplares similares
-
Molecular dynamics and structure-based virtual screening and identification of natural compounds as Wnt signaling modulators: possible therapeutics for Alzheimer’s disease
por: Manandhar, Suman, et al.
Publicado: (2022) -
Antidepressant-like effect of dehydrozingerone from Zingiber officinale by elevating monoamines in brain: in silico and in vivo studies
por: Moorkoth, Sudheer, et al.
Publicado: (2021) -
Repurposing FDA-approved drugs for anti-aging therapies
por: Snell, Terry W., et al.
Publicado: (2016) -
Exploration of small-molecule entry disruptors for chikungunya virus by targeting matrix remodelling associated protein
por: Kumar, Avinash, et al.
Publicado: (2020) -
Computational design of a broad-spectrum multi-epitope vaccine candidate against seven strains of human coronaviruses
por: Kumar, Avinash, et al.
Publicado: (2022)