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Generation of novel trimeric fragments of human SP-A and SP-D after recombinant soluble expression in E. coli

Surfactant treatment for neonatal respiratory distress syndrome has dramatically improved survival of preterm infants. However, this has resulted in a markedly increased incidence of sequelae such as neonatal chronic inflammatory lung disease. The current surfactant preparations in clinical use lack...

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Detalles Bibliográficos
Autores principales: Watson, Alastair, Sørensen, Grith L., Holmskov, Uffe, Whitwell, Harry J., Madsen, Jens, Clark, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422833/
https://www.ncbi.nlm.nih.gov/pubmed/32747028
http://dx.doi.org/10.1016/j.imbio.2020.151953