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Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid.

Background: n-Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyses the NAD (+)-dependent oxidative phosphorylation of n-glyceraldehyde-3-phosphate to 1,3-diphospho-n-glycerate and its reverse reaction in glycolysis and gluconeogenesis. Methods: Four distinct crystal structures of human n-Glyce...

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Detalles Bibliográficos
Autores principales: Lia, Andrea, Dowle, Adam, Taylor, Chris, Santino, Angelo, Roversi, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422855/
https://www.ncbi.nlm.nih.gov/pubmed/32802964
http://dx.doi.org/10.12688/wellcomeopenres.15893.2