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Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis

PURPOSE: The purpose of this study was to determine mesenchymal stem cell (MSC) therapy efficacy on rescuing the visual system in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS) and to provide new mechanistic insights. METHODS: EAE was induced in female C57BL6 mi...

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Detalles Bibliográficos
Autores principales: Gramlich, Oliver W., Brown, Alexander J., Godwin, Cheyanne R., Chimenti, Michael S., Boland, Lauren K., Ankrum, James A., Kardon, Randy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422913/
https://www.ncbi.nlm.nih.gov/pubmed/32855863
http://dx.doi.org/10.1167/tvst.9.8.16