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Effect of Hydration on the Molecular Dynamics of Hydroxychloroquine Sulfate

[Image: see text] Chloroquine and its derivative hydroxychloroquine are primarily known as antimalaria drugs. Here, we investigate the influence of hydration water on the molecular dynamics in hydroxychloroquine sulfate, a commonly used solubilized drug form. When hydration, even at a low level, res...

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Detalles Bibliográficos
Autores principales: Mamontov, Eugene, Cheng, Yongqiang, Daemen, Luke L., Keum, Jong K., Kolesnikov, Alexander I., Pajerowski, Daniel, Podlesnyak, Andrey, Ramirez-Cuesta, Anibal J., Ryder, Matthew R., Stone, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423024/
https://www.ncbi.nlm.nih.gov/pubmed/32869009
http://dx.doi.org/10.1021/acsomega.0c03091