Regional sequence expansion or collapse in heterozygous genome assemblies

High levels of heterozygosity present a unique genome assembly challenge and can adversely impact downstream analyses, yet is common in sequencing datasets obtained from non-model organisms. Here we show that by re-assembling a heterozygous dataset with variant parameters and different assembly algo...

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Detalles Bibliográficos
Autores principales: Asalone, Kathryn C., Ryan, Kara M., Yamadi, Maryam, Cohen, Annastelle L., Farmer, William G., George, Deborah J., Joppert, Claudia, Kim, Kaitlyn, Mughal, Madeeha Froze, Said, Rana, Toksoz-Exley, Metin, Bisk, Evgeny, Bracht, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423139/
https://www.ncbi.nlm.nih.gov/pubmed/32735589
http://dx.doi.org/10.1371/journal.pcbi.1008104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423139/
https://www.ncbi.nlm.nih.gov/pubmed/32735589
http://dx.doi.org/10.1371/journal.pcbi.1008104

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