RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1

Mutations in the gene encoding Ras-associated binding protein 23 (RAB23) cause Carpenter Syndrome, which is characterized by multiple developmental abnormalities including polysyndactyly and defects in skull morphogenesis. To understand how RAB23 regulates skull development, we generated Rab23-defic...

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Detalles Bibliográficos
Autores principales: Hasan, Md Rakibul, Takatalo, Maarit, Ma, Hongqiang, Rice, Ritva, Mustonen, Tuija, Rice, David PC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423339/
https://www.ncbi.nlm.nih.gov/pubmed/32662771
http://dx.doi.org/10.7554/eLife.55829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423339/
https://www.ncbi.nlm.nih.gov/pubmed/32662771
http://dx.doi.org/10.7554/eLife.55829

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